Reproduction Abstracts

Sertoli cells (SC) are key initiators of testis development and have a fundamental role in spermatogenesis. However, it is uncertain how an acute reduction in SC number, in a hormone independent-manner at key points in development or adulthood, will impact testis function.To induce acute SC-ablation at key points of testicular development, we used Cre-loxP recombinase technology and the expression of Diphtheria toxin and its receptor. We utilized these l...

Introduction: What is nature versus nurture? To what extent do genetic inheritance and non-genetic factors contribute to one’s character? This is one of the oldest issues in psychology. To answer this historic question, cloned animals are good models because they have identical genetic information to the donors. Previous studies indicated that cloned animals showed different coat color patterns, noseprints and characters compared to the donors. However, no molecular work ...