Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0003s006 | Symposium 2: New roles for old signalling pathways | SRF2016

PI3K regulation of dormant follicle activation

Kawamura Kazuhiro

PI3K is a family of enzyme involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3K-Akt signaling pathway negatively is regulated by PTEN. Recently, we developed the method for activation of dormant follicles by using in vitro culture of ovarian fragments treated with PTEN inhibitor and PI3K activator (IVA, in vitro activation). We applied this approach to infertility treatm...