Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0003p032 | (1) | SRF2016

Gonadotropins induce expression of versican in porcine oocyte-cumulus extracellular matrix and mural granulosa cells

Nagyova Eva , Salustri Antonietta , Kalous Jaroslav , Kubelka Michal , Camaioni Antonella

Introduction: Versican is a large extracellular matrix (ECM) proteoglycan that regulates adhesion, survival, proliferation and migration of the cells, as well as ECM assembly. In rodent follicles, versican V0/V1 expression increases about 4 h after hCG induction, while in bovine granulosa cells no increase was observed post hCG injection, suggesting that versican expression may varies significantly between species. Interestingly, the versican V1 cleaved product G1-DPEAA accumu...