Reproduction Abstracts

One of our major goals is to identify therapeutics and translate our finding to the clinical setting. Over the past few years, we have been focusing on two epithelial specific genes, CDH1 and WNT7A. CDH1 is a transmembrane glycoprotein, belonging to the cadherin superfamily of cell adhesion molecules. When we conditionally delete Cdh1 in the mouse uterus, infertility results due to disorganized cellular structure of the epithelium and ablation of end...