Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p114 | (1) | WCRB2014

Anti-Mullerian Hormone (AMH) regulates the growth and maturation of primate antral follicles during the menstrual cycle

Xu Jing , Lawson Maralee S. , Bishop Cecily V.

Introduction: Studies in primates indicated that AMH promotes preantral follicle growth, but inhibits antral follicle estradiol (E2) production in vitro. Thus, experiments were designed to investigate the role of AMH on primate follicular development in vivo during the spontaneous menstrual cycle.Materials and methods: Hemi-ovariectomized, adult rhesus macaques (n=5) first received vehicle (control) treatment by intraovarian infusion from cycle ...

ra0001p129 | (1) | WCRB2014

Transcriptome in small antral follicles of monkeys on a western-style diet with/without testosterone

Xu Fuhua , Xu Jing , Bishop Cecily V , Cameron Judy L , Stouffer Richard L

Introduction: Recent studies indicate that dietary habits and hyperandrogenemia influence ovarian function in women. However, data are limited regarding the effects of western-style diet (WSD) and androgen (e.g. T) on follicle development, especially during the early follicular stage, in primates. The current study investigated the impact of WSD alone and with chronic T exposure on gene expression in small antral follicles (SAFs) of macaques.Materials an...