Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p227 | (1) | WCRB2014

Single-cell level dynamics of mouse spermatogenic stem cells after transplantation

Nakamura Yoshiaki , Yoshida Shosei

In mice, a technique was developed in which transplanted spermatogenic stem cells (SSCs) reconstitute complete spermatogenesis in the testes of infertile recipient. However, the dynamics of SSCs during the reconstitution process after transplantation is largely unknown. To dissect post-transplantation dynamics of SSCs, the behavioral process of donor spermatogonia was observed by in vivo live-imaging, and their fate was analyzed at a single-cell resolution. For live-i...