Searchable abstracts of presentations at key conferences on reproductive biology and medicine
Volume 1 | WCRB2014 | Next issue

World Congress of Reproductive Biology 2014

Edinburgh, UK
02 Sep 2014 - 04 Sep 2014

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World Congress on Reproductive Biology 2014, 02 - 04 September 2014; Edinburgh, UK


SRF Plenary Lecture

ra0001s001 | SRF Plenary Lecture | WCRB2014

Polycystic ovary syndrome: follicles and fertility

Franks Stephen

Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility but typically is also associated with insulin resistance, disordered energy balance and a predisposition to develop type 2 diabetes mellitus. Anovulation is characterised by arrest of antral follicles but there is compelling evidence for disordered regulation of the early stages of preantral follicle development in the ovaries of women with PCOS. Dysregulation of local growth factor function a...