ra0001s006 | Testis biology and spermatogenesis | WCRB2014
, Rebourcet Diane
, Smith Lee
Cell ablation is a powerful technique for examining the role of a particular cell type in organ development and function. The utility of the technique is dependent upon the ablation being specific to one cell type and for those of us interested in the testis we have been fortunate that methods have existed for some time to ablate the germ cells and the Leydig cells. Recently we have also developed a transgenic mouse model which expresses the diphtheria toxin receptor (DTR) spe...