Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p147 | (1) | WCRB2014

Expression of pentraxin 3 transcript and protein in porcine preovulatory follicles: comparison of in vivo and in vitro conditions

Nagyova Eva , Nemcova Lucie , Kalous Jaroslav , Salustri Antonietta , Camaioni Antonella

It has been previously shown that multimeric pentraxin 3 (PTX3) is a key component of the cumulus oophorus extracellular matrix. Noteworthy, cumuli from PTX3−/− mice were defective in matrix organization and fertility was impaired. PTX3 binds to both tumor necrosis factor alpha-induced protein 6 (TNFAIP6) and inter-alpha-trypsin inhibitor thereby likely serving as a cross linker for multiple hyaluronan molecules, stabilizing in this way the cumulus oopho...

ra0003p032 | (1) | SRF2016

Gonadotropins induce expression of versican in porcine oocyte-cumulus extracellular matrix and mural granulosa cells

Nagyova Eva , Salustri Antonietta , Kalous Jaroslav , Kubelka Michal , Camaioni Antonella

Introduction: Versican is a large extracellular matrix (ECM) proteoglycan that regulates adhesion, survival, proliferation and migration of the cells, as well as ECM assembly. In rodent follicles, versican V0/V1 expression increases about 4 h after hCG induction, while in bovine granulosa cells no increase was observed post hCG injection, suggesting that versican expression may varies significantly between species. Interestingly, the versican V1 cleaved product G1-DPEAA accumu...