Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p131 | (1) | WCRB2014

Inhibin α induced porcine granulosa cells apoptosis through mitochondrial apoptotic pathway

Li Wan-Hong , Chen Shu-Xiong , Chen Lu , Li Chunjin , Zhou Xu

Inhibin is a heterodimeric gonadal glycoprotein hormone belonging to the TGFβ superfamily that named for its ability to suppress FSH synthesis and secretion from anterior pituitary via a negative feedback. It can regulate proliferation, differentiation, and steroidogenesis of granulosa cells (GCs) through paracrine and autocrine manners. The objective of this study was to investigate the interaction between inhibin α subunit (INHA) and apoptosis of porcine ovarian GC...